The Diamond Lab Publications
Journal Papers
2025
85. “Nanodiamond-Based Sensing: A revolution for biosensors in capturing elusive bio-signals in living cells”, Jiahua Zhang, et al., Zhiqin Chu*, Advanced Drug Delivery Reviews, 221, 115590, 2025.
84. “GaN photonic microchip for label-free monitoring of single-cell calcium dynamics”, Xinhao Hu, et al., Zhiqin Chu*, Devices, in press, 2025.
83. “Nuclear Deformation and Stiffness-Dependent Traction Force Generation Dictate the Migration of Cells under Confinement”, Zheng Wang, et al., Zhiqin Chu*, ACS Applied Materials & Interfaces, 17, 23731-23739, 2025.
82. “A Versatile Method for Nano‐Fabrication on Diamond Film: Flexible Diamond Metasurfaces as a Demonstration”, Yicheng Wang, et al., Zhiqin Chu*, Advanced Optical Materials, 13, 2403429, 2025.
81. “Strain-enhanced responsivity of scalable and flexible diamond UV detector”, Jixiang Jing, et al., Zhiqin Chu*, IEEE Electron Device Letters, 46, 541-544, 2025.
80. “Towards ubiquitous radio access using nanodiamond based quantum receivers”, Qunsong Zeng, et al., Zhiqin Chu*, Communications Engineering, 4, 60, 2025.
79. “Selective Addressing of Versatile Nanodiamonds via Physically-Enabled Classifier in Complex Biosystems”, Yayin Tan, et al., Zhiqin Chu*, Nano Letters, 25, 5679–5687, 2025.
78. “A designer minimalistic model emulates the phase separation-mediated assembly and biophysical cues of extracellular matrix”, Xian Xie, et al., Zhiqin Chu, Nature Chemistry, accepted, 2025.
76. “Scalable Reshaping of Diamond Particles via Programmable Nanosculpting”, Tongtong Zhang, et al., Zhiqin Chu*, ACS Nano, 18, 35405–35417, 2024.
75. “A versatile optoelectronic device for ultrasensitive negative-positive pressure sensing applications”, Xiaoshuai An, et al., Zhiqin Chu*, Chip, 3, 100116, 2024.
72. “Rapid, non-contact identification of organic solvents: Monolithic GaN chips incorporating PDMS/PS photonic crystals”, Gaofei Lu, et al., Zhiqin Chu*, Sensors and Actuators B: Chemical, 420, 136511, 2024.
2024
74. “Scalable production of ultraflat and ultraflexible diamond membrane”, Jixiang Jing, et al., Zhiqin Chu*, Nature, 636, 627-634, 2024.
71. “Quantum-enhanced diamond molecular tension microscopy for quantifying cellular forces”, Feng Xu, et al., Zhiqin Chu*, Science Advances, 10, eadi5300, 2024.
73. “A Diamond Heater‐Thermometer Microsensor for Measuring Localized Thermal Conductivity: A Case Study in Gelatin Hydrogel”, Linjie Ma, et al., Zhiqin Chu*, Advanced Optical Materials, 12, 2401232, 2024.
77. “High-dimensional anticounterfeiting nanodiamonds authenticated with deep metric learning”, Lingzhi Wang, et al., Zhiqin Chu*, Nature Communications, 15, 10602, 2024.
70. “Cross‐Correlated Quantum Thermometry Using Diamond Containing Dual‐Defect Centers”, Madhav Gupta, et al., Zhiqin Chu*, Advanced Sensor Research, 3, 2300103, 2024.
69. “Scalable fabrication of fiber-end microtips containing diamond defects for sensing application”, Ce Bian, et al., Zhiqin Chu*, IEEE Photonics Technology Letters, 36, 15, 2024.
68. “Widefield Diamond Quantum Sensing with Neuromorphic Vision Sensors”, Zhiyuan Du, et al., Zhiqin Chu*, Advanced Science, 11, 2304355, 2024.
67. “Modularity-based mathematical modeling of ligand inter-nanocluster connectivity for unraveling reversible stem cell regulation”, Chowon Kim, et al., Zhiqin Chu*, Nature Communications, 15, 10665, 2024.
66. “Fast dynamic softening of hydrogels increases endogenous cell forces by accumulating mechanical signaling molecules”, Jiapeng Yang, et al., Zhiqin Chu*, Cell Stem Cell, in press, 2024.
65. “Dynamic regulation of cell mechanotransduction through sequentially controlled mobile surfaces”, Wenyan Xie, et al., Zhiqin Chu*, Nano Letters, 24, 7953-7961, 2024.
64. “Photonic control of ligand nanospacing in self-assembly regulates stem cell fate”, Sungkyu Lee, et al., Zhiqin Chu*, Bioactive Materials, 34, 164-180, 2024.
63. “Intelligent quantum sensing with computational neuromorphic imaging”, Chutian Wang, et al., Zhiqin Chu*, Computational Optical Sensing and Imaging, 2024
2023
62. “Super-resolution enabled widefield quantum diamond microscopy”, Feng Xu, et al., Zhiqin Chu*, ACS Photonics, 11, 121-127, 2023.
61. “Multimodal dynamic and unclonable anti-counterfeiting using robust diamond microparticles on heterogeneous substrate”, Tongtong Zhang, et al., Zhiqin Chu*, Nature Communications, 14, 2507, 2023.
60. “Two-Photon Excitation of Silicon-Vacancy Centers in Nanodiamonds for All-Optical Thermometry with a Noise Floor of 6.6 mK·Hz-1/2”, Jiahua Zhang, et al., Zhiqin Chu*, The Journal of Physical Chemistry C, 127, 3013-3019, 2023.
59. “A multilevel optical anti-counterfeiting system based on color space correlated Raman spectroscopy of diamond”, Yau Chuen YIU, Zhiqin Chu*, Advanced Photonics Research, 4, 2200281, 2023.
58. “Super-resolution multicolor fluorescence microscopy enabled by an apochromatic super-oscillatory lens with extended depth-of-focus”, Wenli Li, et al., Zhiqin Chu*, Nature Communications, 14, 5107, 2023.
57. “Identifying and exploring a synthetic antiferromagnetic skyrmion”, Yuelei Zhao, et al., Zhiqin Chu*, Advanced Functional Materials, 33, 2303133, 2023.
56. “Reversible conversions between skyrmions and skyrmioniums”, Sheng Yang, et al., Zhiqin Chu*, Nature Communications, 14, 3406, 2023.
55. “Size-dependent response of cells in epithelial tissue modulated by contractile stress fibers”, Chao Fang, et al., Zhiqin Chu*, Biophysical Journal, 122, 1315-1324, 2023.
54. “Miniature viscometer incorporating GaN optical devices with an ultrawide measurement range”, Yumeng Luo, et al., Zhiqin Chu*, Light: Advanced Manufacturing, 4, 1-8 2023.
53. “Static and dynamic: evolving biomaterial mechanical properties to control cellular mechanotransduction”, Wenyan Xie, et al., Zhiqin Chu*, Advanced Science, 10, 2204594 2023.
52. “An AIEgen/graphene oxide nanocomposite (AIEgen@GO)‐based two‐stage “turn‐on” nucleic acid biosensor for rapid detection of SARS‐CoV‐2 viral sequence”, Qin Zhang, et al., Zhiqin Chu*, Aggregate, 4, e195, 2023.
51. “Millisecond autofocusing microscopy using neuromorphic event sensing”, Zhou Ge, et al., Zhiqin Chu*, Optics and Lasers in Engineering, 160, 107247, 2023.
2022
50. “All-optical modulation of single defects in nanodiamonds: revealing rotational and translational motions in cell traction force fields”, Lingzhi Wang, et al., Zhiqin Chu*, Nano Letters, 22, 7714-7723, 2022.
47. “High-quality diamond microparticles containing SiV centers grown by chemical vapor deposition with preselected seeds”, Tongtong Zhang, et al., Zhiqin Chu*, Journal of Materials Chemistry C, 10, 13734-13740, 2022.
46. “Ultrafast miniaturized GaN-based optoelectronic proximity sensor”, Xiaoshuai An, et al., Zhiqin Chu*, Photonics Research, 10, 1964-1970, 2022.
49. “A Versatile, Incubator-Compatible, Monolithic GaN Photonic Chipscope for Label-Free Monitoring of Live Cell Activities”, Yong Hou, Zhiqin Chu*, Advanced Science, 9, 2200910, 2022.
48. “On-demand, direct printing of nanodiamonds at the quantum level”, Zhaoyi Xu, et al., Zhiqin Chu*, Advanced Science, 9, 2103598, 2022.
45. “Viscosity sensors based on III-nitride optical devices integrated with droplet sliding channels”, Hongying Yang, et al., Zhiqin Chu*, IEEE Electron Device Letters, 43, 2169-2172, 2022.
44. “Event-based vision in magneto-optic Kerr effect microscopy”, Kai Zhang, et al., Zhiqin Chu*, AIP Advances, 12, 095315, 2022.
43. “Emerging Diamond Quantum Sensing in Bio-Membranes”, Yayin Tan, et al., Zhiqin Chu*, Membranes, 12, 957, 2022.
42. “Compact GaN-based optical inclinometer”, Xiaoshuai An, et al., Zhiqin Chu*, Optics Letters, 47, 1238-1241, 2022.
41. “Chip-scale in-situ salinity sensing based on a monolithic optoelectronic chip”, Jixiang Jing, et al., Zhiqin Chu*, ACS Sensors, 7, 849–855, 2022.
40. “A data-mining assisted design of structural colors on diamond metasurfaces”, Jixiang Jing, et al., Zhiqin Chu*, Advanced Photonics Research, 3, 2100292, 2022.
39. “Soft Overcomes the Hard: Flexible Materials Adapt to Cell Adhesion to Promote Cell Mechanotransduction”, Qian Sun, Zhiqin Chu*, Bioactive Materials, 10, 397-404, 2022.
38. “Controlling domain wall and field-free spin–orbit torque switching in synthetic antiferromagnets”, Yuelei Zhao, et al., Zhiqin Chu*, Applied Physics Letters, 120, 222401, 2022.
37. “A metal-ion-incorporated mussel-inspired poly(Vinyl Alcohol)-Based polymer coating offers improved antibacterial activity and cellular mechanoresponse manipulation”, Lingyan Gao, et al., Zhiqin Chu*, Angewandte Chemie, 134, e202201563, 2022.
36. “Ligand mobility-mediated cell adhesion and spreading”, Di Wu, et al., Zhiqin Chu*, ACS Applied Materials & Interfaces, 14, 12976–12983, 2022.
2021
35. “2-in-1 dual-fiber probe integrated with NDs for endoscope-like optical thermometry measurements”, Ce Bian, et al., Zhiqin Chu*, IEEE Photonics Technology Letters, 33, 1321-1324, 2021.
34. “Towards quantitative bio-sensing with nitrogen-vacancy center in diamond”, Tongtong Zhang, et al., Zhiqin Chu*, ACS Sensors, 6, 2077-2107, 2021.
33. “Robust Integration of Nitrogen-Vacancy Centers in Nanodiamonds to Optical Fiber and its Application in All-Optical Thermometry”, Ce Bian, et al., Zhiqin Chu*, Chinese Optics Letters, 19, 120601, 2021.
32. “Scalable fabrication of clean nanodiamonds via salt-assisted air oxidation: implications for sensing and imaging”, Tongtong Zhang, et al., Zhiqin Chu*, ACS Applied Nano Materials, 4, 9223-9230, 2021.
31. “A compact optical pressure sensor based on a III-Nitride photonic chip with nanosphere-embedded PDMS”, Jixiang Jing, et al., Zhiqin Chu*, ACS Applied Electronic Materials, 3, 1982-1987, 2021.
30. “Unveiling a hidden event in fluorescence correlative microscopy by atomic force microscopy nanomechanical analysis”, Massimiliano Galluzzi, et al., Zhiqin Chu*, Frontiers in Molecular Biosciences, 8, 669361, 2021.
29. “Biofilm inhibition in oral pathogens by nanodiamonds”, Tongtong Zhang, et al., Zhiqin Chu, Biomaterials Science, 9, 5127-5135, 2021.
28. “Cross-validated optical thermometry using diamond containing dual-defect centers”, Madhav Gupta, et al., Zhiqin Chu*, Quantum Information and Measurement (QIM) VI, OSA, 2021.
27. “Development of a wide-field quantum diamond microscope for imaging dynamics of cell adhesion”, Feng Xu, et al., Zhiqin Chu*, accepted, Quantum Information and Measurement (QIM) VI, OSA, 2021.
26. “An optical humidity sensor: a compact photonic chip integrated with artificial opal”, Binlu Yu, et al., Zhiqin Chu*, Sensors and Actuators B: Chemical, 349, 130763 (2021).
25. “A waveguide metasurface based quasi-far-field transverse-electric superlens”, Yechuan Zhu, et al., Zhiqin Chu*, Opto-Electronic Advances, 4, 210013, 2021.
2020
24. “Maturation of neural cells leads to enhanced axon-extracellular matrix adhesion and altered injury response”, Xueying Shao, et al., Zhiqin Chu*, Frontiers in Bioengineering and Biotechnology, 8, 621777, 2020.
23. “Beading of injured axons driven by tension-and adhesion-regulated membrane shape instability”, Xueying Shao, et al., Zhiqin Chu*, Journal of The Royal Society Interface, 17, 20200331, 2020.
22. “Ultracompact chip-scale refractometer based on an InGaN-based monolithic photonic chip”, Liang Chen, et al., Zhiqin Chu*, ACS Applied Materials & Interfaces, 12, 49748-49754, 2020.
21. “Controllable ligand spacing stimulates cellular mechanotransduction and promotes stem cell ostegenic differentiation on soft hydrogels”, Man Zhang, et al., Zhiqin Chu*, Biomaterials, 268, 120543, 2020.
2019
20. “Development of indocyanine green loaded Au@Silica core shell nanoparticles for plasmonic enhanced light triggered therapy”, Bokai Zhang, et al., Zhiqin Chu*, Journal of Photochemistry Photobiology A: Chemistry, 375, 244-251, 2019.
19. “Surface roughness and substrate stiffness synergize to drive cellular mechanoresponse”, Yong Hou, et al., Zhiqin Chu*, Nano Letters, 20, 748-757, 2019.
18. “Extrinsic polarization-enabled covert plasmonic colors using aluminum nanostructures”, Lin Cheng, et al., Zhiqin Chu*, Annalen Der Physik, 531, 1900073, 2019.
17. “Surface immobilized E‐Cadherin mimetic peptide regulates the adhesion and clustering of epithelial cells”, Jie Li, et al., Zhiqin Chu*, Advanced Healthcare Materials, 8, 1801384, 2019.
16. “Transformable nanotherapeutics enabled by ICG: Towards enhanced tumor penetration under NIR light irradiation”, Yuxiang Tang, et al., Zhiqin Chu*, Nanoscale, 11, 6217-6227, 2019.
PRIOR TO HKU
15. “Self-assembly of folic acid dextran conjugates for cancer chemotherapy”, Yuxiang Tang, et al., Zhiqin Chu*, Nanoscale, 10, 17265-17274, 2018.
14. “Shape Dependent Cytotoxicity of PLGA Nanoparticles on Human Cells”, Bokai Zhang, et al., Zhiqin Chu*, Scientific Reports, 7, 7315, 2017.
13. “Multidrug Resistance in Cancer Circumvented Using a Cytosolic Drug Reservoir”, Li Fan, et al., Zhiqin Chu*, Advanced Science, 5, 1700289, 2017.
12. “Optical imaging of localized chemical events using programmable diamond quantum nanosensors”, Torsten Rendler, et al., Zhiqin Chu*, Nature Communications, 8, 14701, 2017.
11. “Anchored but not internalized: shape dependent endocytosis of nanodiamond”, Bokai Zhang, et al., Zhiqin Chu*, Scientific Reports, 7, 46462, 2017.
10. “Thin circular diamond membrane with embedded nitrogen-vacancy centers for hybrid spin-mechanical quantum systems”, S. Ali Momenzadeh, et al., Zhiqin Chu*, Physical Review Applied, 6, 024026, 2016.
9. “Rapid endosomal escape of prickly nanodiamonds: implications for gene delivery”, Zhiqin Chu*, et al., Scientific Reports, 5, 11661, 2015.
8. “Unambiguous observation of shape effects on cellular fate of nanoparticles”, Zhiqin Chu*, et al., Scientific Reports, 4, 4495, 2014.
7. “Designing nanoparticle carriers for enhanced drug efficacy in photodynamic therapy”, Zhiqin Chu*, et al., Biomaterials Science, 2, 827-832, 2014.
6. “Controllable drug release and simultaneously carrier decomposition of SiO2-drug composite nanoparticles”, Silu Zhang, et al., Zhiqin Chu*, Journal of the American Chemical Society, 135, 5709-5716, 2013.
5. “Surface plasmon enhanced drug efficacy using core shell Au@SiO2 nanoparticle carrier”, Zhiqin Chu*, et al., Nanoscale, 5, 3406-3411, 2013.
4. “Physiological pathway of human cell damage induced by genotoxic crystalline silica nanoparticles”, Zhiqin Chu*, et al., Biomaterials, 33, 7540-7546, 2012.
3. “Cellular uptake, evolution, and excretion of Silica nanoparticles in human cells”, Zhiqin Chu*, et al., Nanoscale, 3, 3291-3299, 2011.
2. “Synthesis and Transport Properties of Si-doped In2O3(ZnO)3 Superlattice Nanobelts”, J. Y. Zhang, et al., Zhiqin Chu*, CrystEngComm, 13, 3569-3572, 2011.
1. “High-yield Synthesis of In2-xGaxO3(ZnO)3 Nanobelts with a Planar Super lattice Structure”, Lili Wu, et al., Zhiqin Chu*, CrystEngComm, 12, 2047-2050, 2010.
Patents
1. Zhiqin Chu*, et al,, “An efficient purification method for nanodiamonds”, US non-provisional patent Application No. 18/033,080.
2. Zhiqin Chu*, et al., “Methods and apparatus for integrating diamond with LED towards on-chip quantum sensing”, US provisional patent Application No. 63/155,354 (PCT Application No. PCT/CN2022/076011).
3. Zhiqin Chu*, et al., “Photonic chip for monitoring activities of living cells”, US non-provisional application No. 17/846,056.
4. Jitae Kim, et al., Zhiqin Chu*, “Fabrication of a scalable quantum sensing device through precisely programmable patterning spin defects on universal substrates”, US non-provisional patent Application No. 18/686,153.
5. Zhiqin Chu*, et al., “System and methods for ultrafast widefield quantum sensing using neuromorphic vision sensors”, US non-provisional patent Application No. 18/686,153.
6. Zhiqin Chu*, et al., “Methods and apparatus for an anti-counterfeiting system using color space correlated Raman spectroscopy of diamond”, US non-provisional patent Application No. 18/073,227 (CN Patent Application No. 202211531712.7).
7. Ruihui Wang, et al., Zhiqin Chu*, “Method for preparing fiber-based quantum probe using diamond particles with controllable concentration”, CN Patent App. 202011022322.8.
8. Kwai Hei Li, et al., Zhiqin Chu*, “A sensor, device and method for measuring liquid refractive index”, CN Patent App. 202010520069.2.
9. Kwai Hei Li, et al., Zhiqin Chu*, “Monolithic integrated chip and application thereof”, CN Patent App. CN202110915271.X.
10. Zhiqin Chu*, et al., “Physical unclonable functional materials based on diamond particles and preparation and application thereof”, CN Patent Application No. 202210835536.X.
11. Zhiqin Chu*, et al., “Opto chip-based viscometer”, US non-provisional patent application No. 18/588,142.
12. Zhiqin Chu*, et al., “A scalable method for achieving shape control of diamond micro- and nanoparticles”, US non-provisional patent application No. 18/416,325.
13. Zhiqin Chu*, et al., “Scalable fabrication of large-scale, ultraflat and transferable polycrystalline diamond membranes”, CN Patent Application No. 2023105406947.
14. Zhiqin Chu*, et al., “A method for fabricating in large-scale ultraflat polycrystalline diamond membranes”, CN Patent Application No. 202310990328.1.
15. Zhiqin Chu*, et al., “Precise Placement of a Single Diamond Nanoparticles in a Large Area”, US provisional patent Application No. 63/675,053.